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The reduction of tropinone is mediated by NADPH-dependent reductase enzymes, that have been characterized in several plant species.[146] These plant species all consist of two forms of the reductase enzymes, tropinone reductase I and tropinone reductase II.

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After they wished to help make by themselves drunk and from judgment they chewed a mix of tobacco and coca leaves which make them go because they were being out of their wittes.[164]

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